Meta progression guide
Talents are permanent choices that shape every future run. The best setup depends on whether your bottleneck is item consistency, survival, MP, movement or a specific build engine.
Direct answer
There is no single best Talent board. A community discussion favors Luck for more reliable high-value options, while other players invest in Survival, Defense or MP regeneration for consistency. Treat those as build goals rather than a universal ranking.
Use Luck when a route needs rare Artifacts or rerolls; use Defense or Endure when incoming damage ends runs; use MP-focused talents when the Weapon or Companion engine cannot sustain its casts. Re-evaluate after a patch or when switching from solo to co-op.
Resets
The supplied guide records Talent allocations as reversible outside the dungeon through the house mirror or the documented P control. A community support discussion also describes changing Talents in the house. Confirm the current interaction prompt and controller mapping in the live client before a run.
Build presets
These are starting templates. Record the exact point distribution, Costume, Weapon and Hard Mode tier with each successful run so a future balance change is traceable.
Related guides
Read the Destiny Inscription guide for permanent unlock order, compare Hard Mode routes, and use the Preset guide to record a reproducible build.
Verification note
Last verified against the supplied Sephiria research set. Version-sensitive claims retain their source version; missing paths, compatibility details, and current balance values are marked To be confirmed rather than guessed. See the site's research sources for the full method.